Does your protocol require IACUC review?

1. Who Must Submit a Protocol?

All University of Oregon faculty, students, or staff intending to use live or dead vertebrate animals in research or teaching must submit an application for the use of animals (protocol) to the IACUC. 

Strictly observational studies on unconfined animals in the field do not require IACUC approval.

The protocol must be fully approved before an animal user may acquire, house or use animals. 

 

2. Information Required for the Protocol.

Thorough preparation of protocols facilitates the review process and reduces the chance of delay in initiating projects.

Investigators with questions regarding protocol preparation are encouraged to contact AWS.

 

The protocol form requires:

  • a non technical description of the research
  • a justification for the use of animals
  • a description of all procedures to be performed on animals
  • precautions to be taken to guarantee humane care and treatment.

Once approved by the IACUC and subsequently funded by the granting agency, the protocol becomes a public document. Accordingly, investigators should anticipate that the protocol may be reviewed by the general public.

3. Timetable for Protocol Submission.

It is recommended that protocols be submitted at least 90 days before the use of animals is to begin. This lead time is required because protocols frequently require revisions before they can be submitted to the full membership of the IACUC for review. Contact the IACUC office (iacuc@uoregon.edu) for a timetable of IACUC meetings and protocol submission deadlines.

4. The Protocol Review Process

  1.  Initial screening is performed by the IACUC chair, and the staff of the IACUC and AWS. This first review ensures that proposed housing, source of animals, drugs and dosages, and animal use procedures meet NIH Guide standards, comply with federal regulations and campus guidelines and policies.
  2. Following this preliminary review, the IACUC will contact the applicant by email or phone if clarifications or revisions are necessary (many of the protocols received require some clarification or revision).
  3. The original or revised protocol is then distributed to all IACUC members for review.
  4. In some cases, the original or revised protocol may be given to a subcommittee of the IACUC or an outside consultant(s) for further review.
  5. The protocol is voted upon by the full Committee. The Committee can fully approve the protocol, give provisional approval subject to minor changes (in methods, for example), defer a vote until more information is provided, or request a meeting of the full committee.

Approvals:

Approved by date
IACUC Committee May 2022